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QICID: 19190
Title: Application of Analysis of Means (ANOM) to Nested Designs for Improving the Visualization and Understanding of the Sources of Variation of Chemical and Pharmaceutical Processes
Copyright: 2003, ASQ and Marcel Dekker, Inc.
Author: Gonzalez-de la Parra, Mario; Rodriguez-Loaiza, Pilar
Organization: Universidad Nacional Autonoma de Mexico, CU Mexico, DF, Mexico
Subject: Analysis Of Means (ANOM),Case study,Variation,Validation,Design of experiments (DOE);
Series: Quality Engineering, Vol. 15, No. 4, June 2003, pp. 663-670
Abstract: [This abstract is based on the authors' abstract.] The development and validation of chemical and pharmaceutical processes require all sources of variation to be identified and minimized in order to comply with validation requirements. A case study is used to show the value of the application of analysis of means (ANOM) as a visualization tool to complement the conventional analysis of nested designs. The study focuses the interpretation of ANOM charts on the patterns of the means rather than on individual differences among the means. This helps illustrate that ANOM charts are often useful in detecting relations among the nested factors that are critical to resolving quality problems.
Number of pages: 8
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